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Description:Risk factors of the disease can include age Figures reveal the incidence of anal cancer have increased by per cent since the late s. The anus is the part of the bowel that opens to the outside of the body from the rectum and measures about about three cm. Like a number of cancers, the risk of developing the disease increases as people get older. Around nine in ten cases of anal cancer are linked to the HPV infection - human papillomavirus - the same virus that causes the majority of cancers of the cervix, vulva, vagina, penis and oropharynx. Different types of HPV are classed as either high risk or low risk, depending on the conditions they can cause. HPV is transmitted through skin-to-skin contact and people can get HPV by having vaginal, anal, or oral sex with someone who has the virus.