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Description:The publisher's final edited version of this article is available free at Cancer Prev Res Phila See other articles in PMC that cite the published article. Treatment of this cancer is based upon traditional chemoradiotherapeutic approaches, which are associated with high morbidity, and of limited effectiveness for patients with high grade disease. The mammalian target of rapamycin mTOR pathway has been implicated in several human cancers, and is being investigated as a potential therapeutic target. In archival human anal cancers we observed mTOR pathway activation.
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Date: 2018-08-23
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